Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)

Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)
Advanced Embryology Hardik IVF Center

Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)

Service Overview

What is Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)?

What is IMSI Treatment?

Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) is an advanced fertility treatment performed alongside IVF and ICSI. Using a high-powered microscope that magnifies sperm up to 6,000 times, fertility specialists can select the healthiest sperm with the best shape and structure before fertilization. This advanced sperm selection may improve embryo quality and increase the chances of a successful pregnancy, especially in couples with severe male infertility or repeated IVF failure.

Candidate Eligibility

Who Needs Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) Treatment?

Your fertility specialist may recommend treatment if you experience any of the following conditions:

  • Severe male infertility (low sperm count, poor motility, or abnormal sperm)
  • Previous failed IVF or ICSI cycles
  • Recurrent miscarriage
  • Unexplained infertility
  • Women above 38 years of age
  • Couples with poor embryo quality
  • Couples at risk of passing certain genetic conditions
Service Process

How Does Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) Work?

A step-by-step clinical timeline of the procedure at Hardik IVF:

1

Semen Collection

Phase 01

A semen sample is collected and prepared.

2

Advanced Sperm Selection

Phase 02

The healthiest sperm is selected using high-magnification

3

ICSI Procedure

Phase 03

A single selected sperm is injected directly into the egg.

4

Embryo Culture

Phase 04

Fertilized embryos develop in the laboratory for 3–5 days.

5

Embryo Transfer

Phase 05

The healthiest embryo is transferred into the uterus.

Treatment Advantages

Benefits of Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)

Key advantages of choosing Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) for your fertility journey:

  • Advanced sperm selection technology
  • May improve embryo quality
  • Higher fertilization potential in selected cases
  • May reduce the risk of miscarriage
  • Particularly beneficial for severe male infertility and repeated IVF failure
Frequently Asked Questions

FAQs About Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)

Find clear answers to common questions about treatment:

What is IMSI treatment?
IMSI (Intracytoplasmic Morphologically Selected Sperm Injection) is an advanced form of ICSI that uses high-magnification microscopy to select the healthiest sperm before fertilization.
What is the difference between IMSI and ICSI?
Both procedures involve injecting a single sperm into an egg. IMSI uses much higher magnification to examine sperm in greater detail, allowing embryologists to select sperm with the best morphology.
Who should consider IMSI?
IMSI is often recommended for couples with severe male infertility, recurrent IVF or ICSI failure, poor embryo quality, recurrent miscarriage, or unexplained infertility.
Can IMSI improve IVF success rates?
For selected patients, particularly those with male factor infertility, IMSI may improve embryo quality and fertilization outcomes. Your fertility specialist will recommend whether IMSI is suitable for your condition.
Is IMSI safe?
Yes. IMSI is a safe and well-established laboratory technique performed by experienced embryologists as part of IVF treatment.
How much does IMSI treatment cost in Nepal?
The cost of IMSI treatment varies depending on your IVF treatment plan and individual fertility needs. Our specialists will provide a personalized treatment estimate during your consultation.
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