How To Prevent Miscarriage After IVF Treatment In 2025
Mar 2025 Author
IVF

How To Prevent Miscarriage After IVF Treatment In 2025?

Infertility has been a major issue that prevents the dream of parenthood from being fulfilled. Another major issue, in addition to infertility, is miscarriage. While the issue of infertility has been solved with IVF to some extent, miscarriage is still a major issue, even if you choose IVF as a fertility treatment. So, the question here is not infertility but rather how to prevent miscarriage after IVF treatment. Furthermore, you may also want to know the signs, factors, and how to prevent miscarriage after treatment. If you have these questions, then you have come to the right place.  

In this blog, we discuss various aspects of preventing miscarriage after IVF, such as what is miscarriage in IVF pregnancy, causes of miscarriage after IVF, signs and symptoms of miscarriage after IVF, and factors contributing to miscarriage after IVF. In addition to this, we shall also provide you with information regarding how to prevent miscarriage after IVF and miscarriage.  

What Is Miscarriage In IVF Pregnancy?

What Is Miscarriage In IVF Pregnancy

The term miscarriage refers to the sudden loss of pregnancy before the 20th week. This signifies that the miscarriage can occur in a state after an embryo is implanted in the uterus after the IVF treatment 

In terms of IVF, the miscarriage is defined as a loss of pregnancy before the fetal heartbeat is detected, typically around the 6th to 8th week of progression. That said, do note that miscarriage can occur at a later stage of pregnancy as well.  

Now, do note that the chances of miscarriage in IVF are slightly higher when compared to normal pregnancy. The timing of miscarriage can also vary depending on your health, as some can occur as early as a few days after implantation, and others can occur later in the first trimester.  

So, in essence, miscarriage is a condition where a pregnancy is lost after the egg has been implanted into the uterus, typically occurring between the 6th to 8th week but before the 20th week after the implantation.  

Causes Of Miscarriage After IVF 

Now, after discussing what a miscarriage is, let's talk about some of the key causes of miscarriage after IVF. While miscarriages can be heartbreaking and emotionally traumatizing, knowing the cause behind them can help in prevention and better management. The good news here is that we understand miscarriage enough to know its core causes. Some of these core causes of miscarriage after IVF include:  

  • Chromosomal Abnormalities: It is the most common cause of miscarriage, which occurs when the embryo has genetic defects that prevent proper development.  
  • Uterine Abnormalities: It includes conditions such as fibroids, polyps, and thin endometrial lining, which can make implantation difficult.  
  • Hormonal Imbalance: if you have low progesterone levels or thyroid issues, it can affect pregnancy maintenance, which can lead to miscarriage.  
  • Immune System Disorders: Overactive immune responses can lead to the immune system attacking the embryo, which in turn can lead to miscarriage. 
  • Blood Clotting Disorders: Blood Clotting Disorders such as thrombophilia can restrict blood supply to the uterus, leading to the failure of a successful development of the baby and miscarriage.  
  • Lifestyle Factors: Indulging in activities such as smoking, taking in excessive caffeine, high stress, and poor nutrition can also lead to miscarriage. 
  • Maternal Age: if your age is above 35, it can lead to increased chances of miscarriage.  
  • Underlying Health Conditions: Conditions such as diabetes, high blood pressure, or autoimmune diseases can also affect pregnancy outcomes and lead to miscarriage.  

As mentioned prior, these are just some of the major causes of miscarriage after IVF. Besides the ones we mentioned here, there can be many other causes leading to miscarriage. However, the ones we mentioned here are some of the key and common causes.  

Signs And Symptoms Of Miscarriage After IVF 

While miscarriage is devastating, knowing its cause can indeed help you deal with the situation better. Another key aspect that can make this process much better is knowing the key signs and symptoms better. Rather, it is important to be aware of the signs and symptoms of miscarriage after going through the IVF cycle so that you can take swift action at the first sign to prevent further issues. So, what are the key signs and symptoms of miscarriage after IVF? Some of the key signs include:  

  • Vaginal Bleeding: if you see spotting or bleeding in the vagina, ranging from light to heavy, it can be a sign of miscarriage. Rather, vaginal bleeding is one of the most common signs of miscarriage.  
  • Cramping: Another common sign of miscarriage is cramping. If you are having cramps similar to menstrual cramping, often more intense than typical menstrual cramping, then it can be a sign of miscarriage. 
  • Lower Back Pain: If you have persistent lower back pain, which is rather dull and aching, it can be a sign of miscarriage. 
  • Pelvic Pain: Pelvic pain similar to period pain can also occur, and should it occur after IVF treatment, it can signal a miscarriage. 
  • Passing Tissue: If you pass a grayish or pinkish tissue from your vagina, then you can consider it a sign of miscarriage. 
  • Decrease in Pregnancy Symptoms: If you face a sudden decrease in symptoms such as nausea, breast tenderness, or fatigue, which you expect or experience during pregnancy, then it too can be a sign of miscarriage.  

These are some of the key signs and symptoms you should look out for after IVF. Depending on your specific condition, you may experience one or multiple symptoms at once. Should you face these symptoms, then it is recommended to seek medical expertise immediately.  

Factors Contributing To Miscarriage 

Factors Contributing To Miscarriage

In addition to knowing about the signs and symptoms, knowing about some of the key factors can also alleviate a lot of your stress and reduce the chances of miscarriage after IVF. Some of the key factors to note that contribute to miscarriage include:  

  • Age and Egg Quality: The chances of miscarriage increase with the increase in age. The chances get particularly high once the age of 35 is crossed, as after this point, the quality of eggs continues to decline.  
  • Hormonal Fluctuations: In addition to age and egg quality, hormonal fluctuations also contribute to miscarriage. Irregular hormone levels can prevent embryo implantation and hamper development.  
  • Chronic Health Conditions: Pre-existing conditions such as diabetes, high blood pressure, and autoimmune disorders can interfere with pregnancy progression and lead to miscarriage.  
  • Reproductive Anatomy Issues: Factors such as a weak cervix, fibroids, or an abnormally shaped uterus can make it difficult for the embryo to develop properly, leading to miscarriage.  
  • Blood Circulation Problems: Another key factor leading to miscarriage is blood circulation problems, which can include issues such as clotting disorders and poor placental function.  
  • Infections and Inflammation: Specific infections or chronic inflammatory conditions can disrupt the growth of the fetus, which can be a major factor in miscarriage after IVF 
  • Weight and Nutrition: unnatural weight and a nutritional deficiency can also factor into miscarriage after IVF.  
  • Lifestyle and Environmental Factors: This includes factors such as excessive consumption of alcohol and caffeine, alcohol, and smoking.  
  • Excessive Physical and Mental Stress: If you have excessive physical stress, such as the ones from intensive physical exertion, chronic stress, depression, or emotional trauma, it can factor into miscarriage. 
  • History of Pregnancy Loss: If you have a past history of miscarriage, you are more likely to have a miscarriage. Thus, besides present conditions, the past also factors into miscarriage.  

These are some of the key factors which can contribute to or directly lead to miscarriage. Although there are other factors, the ones we covered here are the major and common ones.  

How To Avoid Miscarriage After IVF Treatment? 

Now, at this point, we have discussed some of the key additional information regarding miscarriage after IVF. So, let’s head to the key point and discuss how to avoid miscarriage after IVF treatments. Now, there are many ways you can do this. Some of the key ways on how to prevent miscarriage after IVF include:  

1. Genetic Testing of Embryos (PGT) 

One of the first ways you can prevent miscarriage after IVF is to take preimplantation genetic testing (PGT) during the IVF process. It is a valuable tool that screens embryos for chromosomal abnormalities before implantation. Now, you do have to note that many miscarriages happen due to genetic defects. So, selecting healthy embryos can significantly increase the chances of IVF pregnancy and aid in avoiding miscarriage. It also helps in reducing the chances of implantation failure and increases the likelihood of a full-term pregnancy.  

2. Improving Maternal Health 

While looking for a method of preventing miscarriage, you do have to note your overall health plays an important role in sustaining pregnancy. If you have conditions such as diabetes, hypertension, thyroid imbalances, and autoimmune diseases, it can affect pregnancy. Proper medical management and a well-balanced diet, along with the consumption of prenatal vitamins and regular check-ups, can ensure that the body is in the optimal condition to support fetal development. Furthermore, maintaining a healthy weight also aids in preventing miscarriage after the IVF treatment.  

3. Progesterone and Hormonal Balance  

Hormonal support is also one of the most essential aspects for avoiding miscarriage after IVF treatment. Progesterone, which is a key hormone, aids in preparing the uterine lining for implantation and it also sustains the early stages of pregnancy. Many women who undergo IVF receive progesterone to prevent hormonal imbalances, which can lead to miscarriage. You should also note that regular hormone level monitoring and timely adjustments of supplements and medications can also aid in the prevention or avoidance of miscarriage after IVF.  

4. Treat Uterine Abnormalities 

Another answer to the question of how to prevent miscarriage after IVF is to treat uterine abnormalities. Structural issues within the uterus, such as fibroids, polyps, scarring or weak cervix, can and often do interfere with embryo implantation and development. So, being evaluated for any uterine abnormalities through tests such as ultrasound and hysteroscopy and treating any abnormalities through treatments such as surgery, medications, and corrective procedures can reduce the risk of miscarriage.  

5. Healthy Lifestyle 

Although often overlooked, you should note that a healthy lifestyle is one of the most effective ways to improve pregnancy outcomes and prevent miscarriage. You can do this by avoiding harmful substances such as excessive caffeine and alcohol, tobacco, and nicotine. Furthermore, you should also keep a well-balanced diet rich in essential nutrients, which include folic acid, iron, and omega-3 fatty acids to support fetal growth. You should also keep in mind that although excessive strain is prohibited, you can engage in moderate exercises for a lessened chance of miscarriage.  

6. Advanced Care for Immune Disorders 

Now, although immune disorders are not all that common, if you are someone who is facing immune disorders, one of the best ways to prevent miscarriage after IVF is by taking advanced care for immune disorders. This includes taking treatments such as low-dose steroids, low-dose immunotherapy, and anticoagulants, which support embryo implantations and fetal growth. You should also note that blood thinning medications may also improve placental blood flow if you have clotting disorders. 

These are just some of the key answers to your question of how to prevent miscarriage after IVF. Depending on your circumstances, you may need one or more of these options. 

Consult Hardik IVF: Best IVF Center In Nepal 

Consult Hardik IVF Best IVF Center In Nepal

So, after being aware of what a miscarriage in IVF is, its signs and symptoms, and how to prevent miscarriage in IVF, you may want to know where you can get the best miscarriage treatment in Nepal. Well one of the best places where you can seek miscarriage treatment is Hardik IVF and Fertility Center, one of the top IVF centers in Nepal. But why visit Hardik to avoid miscarriage after IVF? Some of the key reasons are: 

  • Expert Medical Staff: Has access to experienced fertility specialists and obstetricians who have expertise in complicated pregnancies. 
  • High-Tech: Uses the latest technology in the field, such as genetic testing (PGT) and precision therapy to achieve improved pregnancy results. 
  • Individualized Care: Customized care programs based on unique health challenges and pregnancy conditions. 
  • Holistic Philosophy: Helps bring balance to the blend of medical care, lifestyle modifications, and mental support. 
  • 24/7 Care and Support: Offers continuous care for complicated pregnancies. 
  • Success Rate: Established record of success with IVF healthy baby conception. 
  • Patient-Centric: Placing patient comfort, direction, and emotional support at every stage of the pregnancy journey. 

Conclusion 

IVF is also the most successful method of treatment for infertility. However, IVF is not a technique of which results are 100% certain, and even if this is the case, there is a chance of miscarriage. The good thing here is that by getting your lifestyle changed, getting the necessary tests before IVF, and going through necessary medications, you can prevent miscarriage after IVF. Along with this, it would also be helpful if you know about the causes and signs of IVF as they would help you detect a miscarriage earlier in IVF pregnancy so that the experts can take necessary measures. 

In this blog, we provide you with answers on how to prevent miscarriage after IVF, in addition to a few additional pieces of information. We hope you found this helpful. If you seek further insights into the various aspects of IVF, do check out some of our other blogs. And, if you want the best service regarding prevention of miscarriage after IVF, look no further than Hardik IVF and Fertility Center: The best IVF center in Nepal. Thank you for reading till the end. 

FAQs On Prevention of Miscarriage After IVF Treatment 

1. Can I get pregnant naturally after IVF miscarriage? 

Yes, many women can conceive naturally after an IVF miscarriage, depending on their overall fertility health and underlying conditions. Consulting a fertility specialist can help assess the chances and determine the best approach for a successful pregnancy. 

2. How do I know if I miscarried after embryo transfer? 

Signs of miscarriage after embryo transfer may include heavy bleeding, severe cramping, passing tissue, or a sudden loss of pregnancy symptoms. However, only an ultrasound and blood tests can confirm a miscarriage, so it’s important to consult a doctor if any concerning symptoms arise. 

3. What are the symptoms of pregnancy after a miscarriage? 

Symptoms of pregnancy after a miscarriage are similar to any early pregnancy, including nausea, breast tenderness, fatigue, and a missed period. A blood test or ultrasound can confirm the pregnancy and ensure it is progressing normally. 

4. How common is miscarriage after FET? 

Miscarriage rates after Frozen Embryo Transfer (FET) vary but are generally between 10–25%, depending on factors like embryo quality, maternal health, and age. Using genetically tested embryos (PGT) and ensuring a healthy uterine environment can help reduce the risk. 

5. How to Avoid Miscarriage in IVF Pregnancy? 

To minimize miscarriage risk, follow a doctor’s recommendations on progesterone support, lifestyle changes, and managing underlying health conditions. Regular monitoring and early medical intervention can also help sustain a healthy pregnancy. 

6. Is a failed fet considered a miscarriage? 

A failed Frozen Embryo Transfer (FET) is not considered a miscarriage if implantation never occurred. However, if implantation happened and the pregnancy was lost, it would be classified as a miscarriage. 

7. What week is the highest risk of miscarriage? 

The highest risk of miscarriage is in the first trimester, with most occurring before 12 weeks. The risk significantly decreases after detecting a strong fetal heartbeat around weeks 6–8. 

8. Is it common to miscarry after seeing a heartbeat? 

The risk of miscarriage drops after seeing a heartbeat, but it still occurs in about 4–10% of cases, especially if there are genetic abnormalities or maternal health issues. Regular prenatal care and monitoring can help detect and manage potential risks early.