Endometriosis & IVF Treatment Can You Still Get Pregnant
Mar 2025 Author
IVF

Endometriosis & IVF Treatment: Can You Still Get Pregnant?

There are many things to note when you are preparing for parenthood. One such aspect is endometriosis. It is a common condition that affects many women of reproductive age, and it often causes pain and fertility challenges. If you are someone who is diagnosed with endometriosis, then you may even wonder if IVF is possible when you have endometriosis. That said, we do have good news for you. Many women with endometriosis have successfully achieved pregnancy with IVF. So, the relationship between endometriosis and IVF is not as simple as having the issue will definitely cause IVF to fail. However, it does impact the process. So, the question here is, what exactly is the relationship between endometriosis and IVF? Well, if you are curious about this, you have come to the right place.  

In this blog, we explore the various aspects of endometriosis and IVF treatment. This includes aspects such as the effect of endometriosis on IVF, whether it affects IVF implantation, possible risks of IVF with endometriosis, and IVF with endometriosis success rate. Furthermore, we shall also provide you with some ways to improve IVF with endometriosis. But, before we go into these details, let’s understand what endometriosis is first.  

Endometriosis And Infertility 

Endometriosis And Infertility

So, first things first, what is endometriosis? Well, endometriosis is a condition where a tissue that is similar in nature to the lining of the uterus grows outside of it, often on the ovaries, fallopian tubes, or other pelvic organs. This abnormal tissue growth can cause pain, heavy periods, and infertility. It can interfere with the reproductive organs and affect the ability to conceive because of the scarring, adhesions, and inflammation, which blocks the normal function of the ovaries and fallopian tubes.  

Now, it is to be noted that understanding how endometriosis leads to infertility is important for those who are navigating the fertility challenge and seeking effective treatments. It should also be noted that endometriosis does not always lead to infertility and, at times, can just be a minor issue. Regardless, if you are someone who is going on a journey of becoming a parent, you should note down the signs and symptoms of endometriosis so that you can take appropriate measures when necessary. As per Wikipedia, endometriosis affects roughly 10% of reproductive women, and among them, 50% may face infertility.  

Endometriosis Symptoms 

Although many women with endometriosis do not experience any form of symptoms, as the issue progresses, it does generally show symptoms. Some of the key and common endometriosis symptoms include:  

  • Intense or painful menstrual periods 
  • Abdominal discomfort or cramps before and during your period 
  • Pain during or after sexual intercourse 
  • Discomfort while urinating or having bowel movements 
  • Difficulty getting pregnant 
  • Diarrhea or constipation 
  • Tiredness or lack of energy 
  • Bloating or feeling nauseous 

As mentioned previously, not all who face endometriosis see these symptoms, but if you see these symptoms, then it is highly recommended for you to visit an expert immediately.  

Endometriosis And IVF Treatment 

Now that we have covered the basic gist of what endometriosis is, its relation with fertility and some of its key symptoms, let's now take a look at its relation between endometriosis and IVF. You do have to note that endometriosis can have an impact on fertility. The good news here is that IVF can bypass some of the challenges posed by endometriosis by directly freezing an egg outside the uterus and then directly planting the embryo back into the uterus. While IVF can increase the chances of pregnancy when you have endometriosis, you do have to note that there are also other factors that contribute to the overall success of the process.  

Can You Get Pregnant? 

As mentioned prior, IVF can bypass the issue caused by endometriosis. So the answer to the question of whether you can get pregnant or not after doing IVF while having endometriosis is, “Yes, yes, you can get pregnant!” Although endometriosis can make natural conception difficult as it causes inflammation, scarring, or hormonal imbalances, IVF does help you bypass some of these challenges. That said, as mentioned previously, the success of IVF depends on many factors, which include the severity of endometriosis, egg quality, and overall reproductive health.  

If you have any doubts regarding this aspect of endometriosis, it is recommended to consult a reproductive expert. Doing so also helps you to determine the best approach for improving the chances of pregnancy as well.  

Does Endometriosis Affect IVF Implantation? 

So, all in all, does endometriosis affect IVF implantation? The simple answer to this is yes, it does affect IVF implantation, as the relationship between endometriosis and IVF is a bit more complicated than what we have discussed so far. This condition causes tissue that is similar to the uterine lining to grow outside the uterus, which can lead to inflammation, scarring, and adhesions. These effects of endometriosis can lead to a less-than-ideal environment for embryo implantation, which in turn affects the ability of the uterine lining to support pregnancy. In addition, endometriosis can also cause hormonal imbalances that interfere with the natural menstrual cycle and ovarian function, which can potentially reduce egg quality. It can also damage the fallopian tubes, which makes it harder for eggs to travel to the uterus.  

That said, do note that many women with endometriosis can still achieve successful pregnancy with IVF. This is especially the case when you get proper treatment for managing the conditions. Approaches such as surgical removal of endometriosis lesions and medications to reduce inflammation can improve the chances of implantations. Although endometriosis can pose challenges, advances in IVF techniques offer solutions for women affected by endometriosis.  

So, yes, endometriosis does impact IVF implantation, but it doesn’t necessarily prevent this process from getting the desired result. Depending on your individual circumstances and the degree of endometriosis, you can still get a successful implantation despite endometriosis.  

Impacts Of Endometriosis 

Impacts Of Endometriosis

Endometriosis can have a wide range of impacts on your physical, emotional, and reproductive health. It goes without saying that endometriosis has impacts on IVF as well. Some of the key ways on how it can influence IVF outcomes include: 

  • Reduced Ovarian Reserve: Endometriosis in advanced stages can affect ovarian function by causing function by causing damage to ovaries. This can result in a reduced ovarian reserve, which further signifies that there can be fewer healthy eggs available for fertilization.  
  • Impaired Egg Quality: The inflammation and hormonal imbalance can also reduce the quality of the eggs. You do have to note that it is important for successful fertilization and embryo development.  
  • Tubal Damage: Depending on the circumstances, endometriosis can also cause scarring or blockages in the fallopian tubes, which makes it harder for the eggs to be retrieved by the IVF. This form of damage can also impact how embryos plant into the uterus during the IVF procedure.  
  • Uterine Environment: Endometriosis can also create an unfavourable uterine environment for embryo implantation. This condition also leads to inflammation and changes in the lining of the uterus, which makes it less receptive to fertilized embryos, which increases the likelihood of implantation failure.  
  • Increased Risk of Miscarriage: if you have endometriosis, you may also face a higher chance of miscarriage, impacting IVF success. While the causes for this are not confirmed, they are thought to be related to immune system dysfunction, hormonal imbalances, and poor uterine environment.  
  • Longer Time to Pregnancy: Endometriosis can delay pregnancy, and women who face these conditions can have a longer duration of pregnancy. The time it takes to achieve a viable pregnancy depends on the severity of endometriosis and how well it is managed.  
  • Need for Additional Treatments: If you have endometriosis, you may also require additional treatments during IVF treatments. These treatments include additional medications to remove endometriosis lesions, hormone therapy to optimize the uterine environment, and more.  

As mentioned previously, despite these impacts on IVF, you can achieve a successful pregnancy and even conceive a healthy child, albeit with some difficulty.  

Possible Risks Of IVF With Endometriosis 

Now, after knowing the impacts of IVF with endometriosis, let's discuss some of the key risks that you may face when doing this treatment when you have endometriosis. So, what exactly are the risks of IVF with endometriosis? Well, some of the most common risks associated with IVF while doing it when you have endometriosis include:  

  • Lower Ovarian Response: Endometriosis can reduce the ovarian reserve, which can further lead to fewer eggs being retrieved during the IVF process.  
  • Implantation Challenges: This issue can also cause inflammation in the uterus and uterine abnormalities, which can lower implantation rates. 
  • Ovarian Cysts and Stimulation Risks: Endometriosis can cause ovarian cysts, which can interfere with egg retrieval. Additionally, ovarian stimulation can cause discomfort and cyst growth, which can further affect egg retrieval.  
  • Pelvic Pain and Inflammation: IVF medications while having endometriosis can worsen pain as a result of increased estrogen levels.  
  • Higher Miscarriage Risk: There is also a slightly increased risk of miscarriage when doing an IVF treatment while having an endometriosis. 
  • Ectopic Pregnancy: Endometriosis can affect the fallopian tube function, which increases the risk of an ectopic pregnancy.  

These are just some of the key risks that you may face when doing an IVF while having endometriosis. Besides the ones we mentioned here, there can also be other issues depending on the specifics of your circumstances.  

IVF With Endometriosis Success Rate 

So, after knowing all of the information we have provided so far about IVF with endometriosis, you may wonder, what are the success rates of IVF with endometriosis? Well, the specific success rate depends on the severity of the condition and whether it is treated or not. So, keeping this in mind, the following are estimated success rates of IVF with endometriosis in various circumstances.  

  • IVF done on Mild to Moderate Endometriosis (state I and 2): The success rate of IVF live births when it is done on mild to moderate endometriosis is roughly around 67.7% (CNY Fertility).  
  • IVF done on Mild to Severe Endometriosis (state 3 and 4): The live birth rate of IVF when it is conducted on mild to severe endometriosis is somewhere around 27.7% if left untreated (Medical News Today).  
  • Impact of Treatment: do note that it is highly recommended for you to go through endometriosis treatment if you face mild to severe endometriosis. Doing so can increase the rate of live births from around 27% to somewhere between 43.6% to 46.3 % (Medical News Today).  

It goes without saying that although the live birth rate is still possible when you have endometriosis, it is highly recommended for you to go through proper treatment should it get severe. Doing so not only increases your overall health but also enhances your birth rate.  

How To Improve IVF With Endometriosis? 

Now, while there are indeed risks and a lowered chance of successful live birth when you do IVF with endometriosis, the good news here is that there are some ways you can improve these chances. Some of the key ways on how you can improve IVF with endometriosis include: 

  • Pre-IVF Treatment: You can use laparoscopic surgery to remove the endometriotic lesions and cysts to improve outcomes, especially for severe cases. 
  • Hormonal Suppression: You can also use GnRH agonists for 2 to 6 months before IVF to reduce inflammation and enhance the implantation rates 
  • Optimization of Ovarian Stimulation: You can also choose a customized IVF protocol for aiding in maximizing egg quality while reducing the risks. 
  • Lifestyle Changes: Another way of improving the IVF success rate with endometriosis is to take a healthy diet, do regular exercise, and engage in stress management to enhance general fertility. 
  • Supplements: You can also take in supplements such as CoQ10, Vitamin D, and omega-3 fatty acids to improve egg quality and reduce inflammation. 
  • Endometrial Preparation: You can also use techniques such as endometrial scratching or frozen embryo transfer, also known as FET, cycle for improved implantation. 
  • Specialist Care: One of the best ways to improve the success rates of IVF with endometriosis is to take the aid of specialists for a personalized approach. 

Do note that depending on your circumstances, you may need to take one or a combination of these measures to improve the success rate. 

Choose Hardik IVF For Best IVF Treatment In Nepal 

Choose Hardik IVF For Best IVF Treatment In Nepal

Now, at this point, we have already covered the general overview of what endometriosis is and the relationship between endometriosis and IVF. So, let's talk about where you can get the best treatment for endometriosis in Nepal. Well, among many places where you can get the treatment, one of the best options you have is Hardik IVF and Fertility Center: The best IVF centre in Nepal. But why choose Hardik? Well, some of the key reasons why you should choose Hardik for the best IVF treatment in Nepal, including when you have endometriosis, include: 

  • Expert Specialists: Hardik boasts a team of very experienced fertility specialists who deal with tough cases like endometriosis and infertility. 
  • Latest Technology: The centre uses the latest IVF technologies, including pre-IVF hormone stimulation and optimal ovulation induction, to maximize success. 
  • Personalized Treatment Plans: Every patient is given a personalized treatment plan formulated according to his/her condition for optimal results. 
  • Holistic Care: From initial diagnosis to post-IVF care, Hardik provides holistic fertility care through laparoscopic surgery and endometriosis hormonal therapy. 
  • Expert Specialists: Hardik uses expert fertility specialists having a couple of years of experience and working with difficult cases like endometriosis and infertility. 
  • Higher Success Rates: With exclusive attention on evidence-based counseling and the latest fertility methods, Hardik has guaranteed conception in several couples. 
  • Sensitive Response: Being aware of the emotional pain associated with infertility, Hardik's team adopts a sensitive response throughout. 

Conclusion 

Endometriosis is a rather common issue that affects the majority of the female population. This issue is essentially a condition where a tissue lining similar to the ones found inside the uterus develops outside the uterus, causing issues for reproduction. Since this issue is associated with reproduction, it goes without saying that it affects IVF as well. Rather, the impact of endometriosis on IVF is well known, along with its risks and ways to improve the chances of success. 

In this blog, we provide you with an overview of the relationship between endometriosis and IVF. We hope that was informative. If you want information on various things related to IVF, do read through some of our other blogs. And, if you want the best IVF treatment in Nepal, even if you are suffering from endometriosis, look no further than  Hardik IVF and Fertility Center. Thank you for reading till the end. 

FAQs On Endometriosis And IVF Treatment 

1. Can you get IVF if you have endometriosis? 

You can get IVF if you have endometriosis, and it is typically an effective treatment for infertility due to endometriosis. However, depending on the severity, pre-IVF treatments like hormonal therapy or surgery can increase success rates by reducing inflammation and optimizing the uterine environment. 

2. What is the success rate of IVF in endometriosis patients? 

Endometriosis patients have IVF success rates that depend on severity, and cumulative live birth in mild endometriosis is approximately 67.7%, while for severe endometriosis it is approximately 27% after repeated cycles. Proper management prior to IVF, like hormonal treatment or surgery, may enhance results. 

3. What is the optimal protocol for IVF with endometriosis? 

A long regimen of GnRH agonists for 2–6 months before ovarian stimulation is generally recommended to reduce inflammation and enhance implantation. Treatment individualized based on the severity of endometriosis yields the best result. 

4. Can IVF cause endometriosis? 

IVF itself does not cause endometriosis, but ovarian stimulation can worsen established endometriosis or trigger recurrence of symptoms in a few women. Cautious monitoring and individualized treatment protocols might avoid untoward effects. 

5. Is there a chance of successful pregnancy with endometritis? 

Yes, but if untreated, endometritis can lower implantation rates and increase the risk of miscarriage, so treatment is essential prior to pregnancy. Endometritis can be eradicated and pregnancy enhanced by antibiotics or other therapy.  

6. Does endometrium affect fertility? 

Yes, there is a need for a healthy endometrium to accept an implanting embryo, and states of thin lining, chronic inflammation, or scarring may decrease fertility. Treatment with hormonal therapy or endometrial preparation techniques may improve the outcome of implantation.